Increased risk of MS in colder climes
Multiple sclerosis (MS) is a neurological disorder. At its root is degeneration
of the fatty sheaths that surround the nerve fibres in the brain and spinal
column. The degeneration of these sheaths (known as myelin sheaths) disrupt
neurological function, and can manifest in any number of ways including physical
disability and impaired brain function. It』s been noted that populations further
from the equator have increased risk of MS compared to those closer to it.
Perhaps not surprisingly, these have led some to investigate the role of vitamin
D and sunlight in relative protection from MS.
It is generally believed that MS is 「autoimmune」 in nature – which means it』s
caused by the body』s immune system reacting against its own tissues (in this
case, the myelin sheaths). There has been evidence published in July 2008 in the
Journal of Cellular Biochemistry that suggests that vitamin D has the capacity
to modulate the immune system in a way that can dampen any tendency to
autoimmunity.
However, new evidence has come to light that at least some of sunlight』s
apparent ability to protect against MS is not down to vitamin D at all.
UV light suppresses MS
The study in question published in the Proceedings of the National Academy of
Sciences in March 2010 used an 「animal model」 of MS known as experimental
autoimmune encephalomyelitis (EAE). In this study, laboratory animals with this
condition were exposed to ultraviolet (UV) light. This led to dramatic
reductions in the activity of the disease. However, the UV light only brought
about a small and transient rise in vitamin D levels in the animals. The
magnitude and duration of this rise would be insufficient to account for the
considerable benefit conferred by the light.
The authors of this study conclude that, 「These results suggest that UVR
[ultraviolet radiation] is likely suppressing disease independent of vitamin D
production, and that vitamin D supplementation alone may not replace the ability
of sunlight to reduce MS susceptibility.」
Before we get too ahead of ourselves, let us bear in mind that this is an animal
model of MS, and only one experiment. However, what it does do is open up the
possibility that some, possibly many, of sunlight』s apparent wide spectrum of
benefits for the body are not mediated through vitamin D, but by other
not-well-understood mechanisms.
Personally, I』m going to continue supplementing with vitamin D. But I』m also
going to do my best to get as much sunlight exposure as I can (without burning)
too.
Dr John Briffa is a London-based doctor, author and health writer with a special
interest in nutrition and natural medicine. Practical advice about all aspects
of health and wellbeing can be found at www.drbriffa.com
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